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The 6 Best Flea And Tick Treatments For Dogs In 2024, With Advice From Vets

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The best flea and tick treatments for dogs are essential for protecting your pet against harmful parasites. Many dog flea and tick preventatives also treat lice and prevent heartworm infections. These safe and effective medications come in the form of topical spot-ons, chewable tablets, shampoos, and collars.

To make our picks for the top flea and tick treatments, we asked veterinarians how to best manage parasites in puppies and adult dogs. Then we researched products using the Companion Animal Parasite Council's quick product reference guide. Our top pick is Advantage Multi, a prescription medicine that prevents and controls fleas and protects against heartworm. If you're looking for an over-the-counter (OTC) medicine, we recommend Frontline Plus for dogs, a topical flea and tick treatment that you apply once a month.

It's important to ask your veterinarian what type of flea and tick preventative is best for your dog. The ideal product depends on your dog's temperament, lifestyle, and the most common parasites where you live. 

Read more about how Business Insider Reviews tests and researches pet products.

Our top picks for the best flea and tick treatments for dogs

Best topical preventative overall: Advantage Multi for Dogs - See at Chewy

Best OTC topical preventative: Frontline Plus for Dogs - See at Chewy

Best pill: Simparica TRIO - See at Chewy

Best for young puppies: Capstar for Dogs - See at Chewy

Best collar: Seresto Flea and Tick Collar for Dogs - See at Chewy

Best shampoo: Adams Plus Flea and Tick Shampoo with Precor - See at Chewy

Best topical preventative overall Advantage Multi for Dogs

With just one easy monthly application, Advantage Multi for Dogs treats, controls, and prevents more parasites than any other topical product.

Not even the best flea medicines control every harmful parasite, but Advantage Multi for Dogs comes close. It's also one of our top picks for the best flea and tick treatments for puppies.

Advantage Multi is a topical spot-on product that contains the active ingredients imidacloprid and moxidectin, which prevent flea infestations by killing adult fleas before they can lay eggs. It also prevents heartworm, mange mites, and three intestinal parasites (roundworms, hookworms, and whipworms). But if your dog already has worms, your vet may recommend treating them with one of the best dog dewormers. As with all medications that prevent heartworm, your dog needs a heartworm test before starting Advantage Multi and annually after that.

Advantage Multi is easy to use: Every 30 days, apply it to your dog's skin at the base of their neck between the shoulder blades. The liquid medication is absorbed and dries within hours. Unlike other topical preventatives, you don't need to wear gloves to apply Advantage Multi. If you get the product on your hands, just wash them with soap and water. For a half-hour after application, keep dogs from licking the application site, either on themselves or other treated dogs. Children should not touch the application site for two hours.

Advantage Multi does not prevent ticks. If you need to control ticks, consider Frontline Plus for Dogs, Bravecto Topical for Dogs, or K9 Advantix II.

Best OTC topical preventative Frontline Plus for Dogs

Available without a prescription, Frontline Plus for Dogs kills adult fleas, flea eggs, flea larvae, ticks, and chewing lice on contact.

Among the best flea and tick treatments for dogs, Frontline Plus is our top pick because it kills ticks and fleas, controls flea infestations, and kills chewing lice with one easy application. Each dose of Frontline Plus lasts up to three months for flea control. If you're concerned about ticks or biting lice, apply it monthly.

Frontline Plus has been used and trusted by pet owners for over 20 years. Parasites do not have to bite your dog for the treatment to work because the medicine works on contact. Its active ingredients, fipronil and S-methoprene, work together to kill parasites and break the flea life cycle. Fipronil kills adult fleas and ticks, while S-methoprene prevents flea eggs, larvae, and pupae from developing. If your pet has a lot of fleas, it can take up to a month of consistent use to get rid of them because flea eggs can be in your home but not on your dog.

Frontline Plus is easy to use. Squeeze all the liquid in the tube onto one spot of your dog's skin between the shoulder blades. The liquid medication spreads across the skin and gets stored in their oil glands. Then it distributes itself continuously via the hair follicles.

Best pill Simparica TRIO for Dogs

Simparica TRIO treats, controls, and prevents more parasites than any other oral product, offering a full month of protection with one easy-to-give flavored pill.

Simparica TRIO is our pick for the best flea and tick treatment for dogs in pill form. The fast-acting chewable tablet kills more parasites than any other oral product. It starts to work within four hours and kills 100% of adult fleas on dogs within eight hours.

It may be tough to choose between an oral or topical flea control product because there are pros and cons to each type of product. In some cases, an oral preventive is a better choice. For instance, some dogs with sensitive skin can't tolerate spot-on treatments. "Oral products have the benefit of broad coverage to reach every spot of skin without the chance of the product being washed off," says Dr. Kate Crumley, a veterinarian with Blue Heron Consulting.  

You can give the liver-flavored tablets with or without food once a month. The treatment contains three ingredients (sarolaner, moxidectin, pyrantel) and provides an entire month of protection against more parasites than any other oral product. Simparica TRIO is also safe for some of the youngest puppies and smallest dogs. It requires a prescription from your veterinarian and a negative heartworm test. You should use it with caution if your dog has a history of neurologic disorders such as seizures.

Best for young puppies Elanco Capstar for Dogs

Capstar for Dogs is safe for puppies as young as 4 weeks old and starts killing fleas within 30 minutes.

You want to eliminate fleas as quickly as possible if your dog has a heavy infestation, especially if they're a young puppy. Available without a prescription, Capstar for Dogs is the only flea control product safe for puppies as young as 4 weeks and weighing at least 2 pounds. With other topical and oral flea control medicines, puppies must be at least 8 weeks old and sometimes older. 

The active ingredient in Capstar, nitenpyram, works within 30 minutes and kills more than 90% of adult fleas in as little as four hours. It only protects for 24 hours, but it is safe to give daily if necessary. Daily dosing is helpful for young puppies who might not be old enough for an oral or spot-on treatment that provides long-term protection.  Once your puppy is old enough, you should follow up with a flea control product that provides a month or more of protection.

Best collar

Editor's note: A March 2021 investigation by USA Today reported 1,700 animal deaths and other adverse reactions linked to Seresto flea collars. It's unknown if the EPA-approved pesticides used in the collar caused these incidents. You can read more about the safety of Seresto collars in our FAQs.

Flea collars were once the go-to method for flea control, but most collars don't offer the same level of protection as topical and oral treatments. One noteworthy collar is the Seresto Flea and Tick Collar for Dogs, which uses sustained-release technology to provide eight months of continuous protection against adult fleas, flea larvae, four species of ticks, chewing lice, and mange mites.

In general, the best flea and tick treatments for dogs are topical spot-on and oral preventatives, but the Seresto collar might be a good option in certain situations. Dr. Kelley Lay, a relief veterinarian in Nashville, Tennessee, says that traditional flea and tick collars are generally not very effective. She has even seen allergic reactions and other issues with some of them. However, she says the Seresto collar is safe and effective and recommends it to clients with pets who don't tolerate topical or oral flea and tick preventives.

The collar is nongreasy, odor-free, lightweight, and adjustable for dogs of all sizes. Your dog can wear it alongside their regular collar, and it has a safety system to keep them safe if the collar gets caught on something. The collar's active ingredients, imidacloprid and flumethrin, are released in low concentrations over your dog's skin and coat to kill fleas and ticks on contact within 24 hours. You don't need to remove this water-resistant collar during swimming or bathing with one of the best dog shampoos.

Best shampoo

Adams Plus Flea and Tick Shampoo is our top pick for the best flea and tick shampoos for dogs. In addition to killing fleas, flea eggs and larvae, ticks, and lice for up to 28 days, the shampoo soothes skin that has become dry and irritated from flea bites and constant scratching. 

The shampoo contains synthetic pesticides commonly included in flea and tick shampoos: pyrethrins and S-methoprene (Precor). It also contains piperonyl butoxide to enhance the effectiveness of those pesticides. Oatmeal helps heal irritated and itchy skin, and the shampoo has a pleasant coconut scent. 

Lay says flea shampoos are fine to use alongside prescription flea control medications. However, shampoos shouldn't be considered the first or best line of defense against fleas. Veterinarian-prescribed, year-round prevention remains the gold standard. Despite marketing claims, these shampoos don't provide substantial flea protection after the bath, so your dog may be susceptible to repeated infestations. Some ingredients in shampoos can also irritate the skin.

What to look for in flea and tick treatments for dogs

Safety and efficacy: FDA- or EPA-approved products have undergone rigorous safety and efficacy testing before going to market.

Number of parasites treated: Using a product that protects against more than just fleas is convenient. While your veterinarian can advise you on which product is best for your dog, we generally favor products that cover more parasites. 

There are some exceptions. For instance, Capstar treats only fleas, but it is the only medicine available for puppies younger than 6 weeks. OTC products, like Frontline Plus, protect against additional parasites such as ticks and lice but not heartworms. Products that treat heartworm always require a veterinary prescription.

Ease of use: The easier it is to use a product, the better. For example, chewable tablets are quick and easy to give your dog, provided they like the flavor. Products that require a person to wear gloves when they apply it or require the treated animal to stay away from children or other pets for a while may be a hassle. 

Minimum age and weight: Flea treatments are intended for dogs above a minimum age and weight. Your options for a very young puppy will be more limited until they are older and weigh more. 

Prescription vs. Over-the-counter: Some flea control products are available over the counter. Others require a prescription from your veterinarian. You can buy prescription medicines from your veterinarian or online pet pharmacies and stores like Chewy, Petco, and PetSmart.

Prescription flea control products typically cost more than OTC options because they protect against more parasites, most importantly, deadly heartworms. Dogs must test negative for heartworms before starting a heartworm preventive. 

Types of flea and tick medications: There are several types of treatments, including topical, oral, collars, shampoos, and sprays. Cost, convenience, ease of use, and effectiveness vary among these products. Your vet can help you determine the best type for your dog. We advise against flea sprays because topical spot-ons and oral products are more effective. Remember that some dogs with sensitive skin may not tolerate topical products. Crumley says that frequent bathing or swimming may also reduce the effectiveness of a topical product that remains on the skin's surface.

Natural vs. Synthetic: Our experts do not recommend using natural products instead of veterinarian-recommended topical and oral flea control. While natural treatments can deter fleas and ticks, they won't eliminate an infestation. "If you use them, be prepared to apply them at least daily before your pet goes outside for the best chance of keeping the hitchhikers from latching on," Crumley says. If you also have kitties at home, avoid natural flea control products containing essential oils because some can be toxic to cats.

Other pets in your home: Any product labeled for use in only dogs should never be given to a cat. Some ingredients can be toxic to cats. While any dog-only flea product can harm felines, cats are especially sensitive to pyrethrins. If you're looking for a safe product for your cat, check out our guide to the best flea and tick treatments for cats.

How we selected the best flea and tick treatments for dogs

We consulted two veterinarians for advice regarding the treatment and prevention of fleas and other parasites in dogs. This information guided our selection of the best flea treatments for dogs, but our experts did not endorse any of the products included in this guide unless explicitly quoted.

We also conducted research using the quick product reference guide published by the independent, nonprofit Companion Animal Parasite Council. This helpful reference includes all FDA- and EPA-approved parasite control products for small animals along with each product's active ingredients, directions for how to use it, and which parasites it controls.

Dog flea and trick treatments FAQs What do vets recommend to get rid of fleas?

Getting rid of fleas can take several days to weeks. Veterinarians recommend a multipronged approach: Kill the existing fleas, prevent new infestations, and treat the environment, both indoors and outside. If you have multiple pets, treat them at the same time. Treating inside your home involves vacuuming where flea eggs and larvae like to hide, such as cracks and crevices, and washing bedding in hot water. Treating outdoors involves eliminating any areas where fleas could hide, such as piles of leaves and tall grass. If this process seems daunting, you can hire a pest control service.

What is the most effective flea treatment for dogs?

There is no single treatment that works best for all dogs. The best flea and tick treatments for dogs vary in many ways, including how many parasites they target, active ingredients, safety restrictions, and how long they're effective. The most desirable treatments provide long-lasting protection, target adult fleas as well as eggs and larvae, and are effective against other parasites, such as heartworm and intestinal worms. Your veterinarian can help you select the most appropriate product for your dog.

Do dogs really need flea and tick medicine?

Yes. Not only are fleas and ticks a big nuisance, they also carry diseases that can make dogs extremely ill. Although you may be tempted to use parasite preventives only in spring and summer, fleas, ticks, mosquitoes, and intestinal parasites are resilient. Veterinarians recommend that dogs stay on broad-spectrum parasite preventives all year.

What are the types of flea and tick medicine for dogs?

Flea and tick medicines are available as oral and topical products, collars, and shampoos. Oral products are chewable tablets, while topical products are ointments that go directly on the skin. Flea collars have fallen out of favor because they are less effective than oral and topical treatments. Shampoos are also less effective and do not provide long-lasting flea protection. These medicines are available over the counter or by prescription and contain different active ingredients to kill and repel fleas and ticks. 

What kills fleas permanently?

To eliminate fleas permanently, you'll need to do more than kill adult fleas. The other developmental stages, egg and larvae, must also be eliminated. Products that kill the early stages of fleas are the most effective. Year-round flea and tick treatment is also crucial to preventing future infestations. It may take several weeks before all the fleas are gone.

Which is better, NexGard or Frontline?

Both NexGard and Frontline kill fleas at all life stages, plus ticks. Both treatments have their advantages. There are several Frontline products: Shield, Plus, and Gold. Our top choice for an OTC flea preventive is Frontline Plus, which also protects against chewing lice and helps control sarcoptic mange infestations. Compared to Frontline Plus, NexGard kills fleas more quickly (4 hours versus 12 hours) and ticks (24 hours versus 48 hours). For this reason, NexGard is a better choice for preventing the transmission of Lyme disease from ticks. Some veterinarians also use NexGard to treat mange.

What is the safest flea and tick medicine for dogs?

Flea and tick medicines are FDA-approved to be safe and effective. However, these medicines also have safety restrictions depending on age, weight, and whether a dog is pregnant or nursing. Some treatments also have safety warnings for dogs with a history of seizures or other neurologic disorders. As you evaluate flea and tick medicines, check the label to ensure it's safe for your dog. 

What is the difference between prescription and OTC flea medicine?

Some flea control products are sold over the counter, while others require a prescription. Prescription products typically cost more than OTC treatments because they protect against more parasites, including heartworms. However, OTC options can still provide effective, long-lasting treatment against fleas and other parasites.

Can I get flea and tick medicine without a vet prescription?

Yes, OTC treatments are available without a prescription. These medicines usually do not protect against as many parasites as prescription flea and tick products.

Do flea collars work?

Yes. Flea collars work but are generally less effective than topical or oral treatments. Seresto Flea and Tick Collar for Dogs provides eight months of protection against adult fleas, flea larvae, ticks, and mange mites. Lay recommends flea collars for dogs that cannot tolerate topical or oral flea products. 

Is Seresto harmful to dogs?

In March 2021, USA Today and the Midwest Center for Investigative Reporting published a report alleging that the Seresto flea collar is linked to thousands of adverse incidents in pets and humans. To date, 2,500 pet deaths have been allegedly linked to the collar.

Elanco published a statement defending the collar's safety and efficacy. The American Veterinary Medical Association (AVMA) and Pet Poison Hotline followed suit. The EPA recommends pet owners read the entire label before using any flea collar and follow all directions carefully. Your veterinarian can provide additional safety guidance. Purchase a Seresto collar only from a reputable online retailer, brick-and-mortar store with a guarantee program, or your veterinarian. To verify product authenticity, call Elanco product support at 800-422-9874. If your pet has an adverse reaction, immediately remove the collar and call your veterinarian. Tim Carroll, EPA's press secretary, advises pet owners to contact the  National Pesticide Information Center and report adverse reactions to the EPA.

How can I tell if my dog has fleas?

Fleas are hard to see with the naked eye. Look for signs of a flea infestation on your dog, including nonstop biting, scratching, or licking and red, irritated skin. Flea dirt, a rust-colored mixture of blood meal and dried feces, is a telltale sign of fleas and can be found in places your dog spends time, such as their bed. Running a flea comb against the direction of your dog's fur can pick up the dirt. You can often see it on your dog in hard-to-reach places like the base of the tail, middle of the back, and groin. Other signs include pale gums, which are a sign of anemia, and patches of hair loss. 

Jackie Brown

Freelance Writer

Pet expert Jackie Brown has spent 20 years following her passion for animals as a writer and editor in the pet industry. Her expertise includes dog and cat health, care, nutrition, feeding, grooming, behavior, and training. Jackie writes regularly for pet and veterinary industry media, including Dogster and Catster magazines, The Spruce Pets, Great Pet Care and All About Cats.   She is a contributing writer for "National Geographic's Complete Guide to Pet Health, Behavior, and Happiness" and author of the book "It's Raining Cats and Dogs: Making Sense of Animal Phrases." She is contributing editor of Dogster and Catster magazines, and the former editor of numerous pet magazines, including Dog World, Natural Dog, Puppies 101, Kittens 101, and the Popular Cats Series.   Jackie earned her bachelor of arts degree in English from the University of California, Irvine. Prior to starting her career in publishing, she spent eight years working in veterinary hospitals where she assisted veterinarians as they treated dogs, cats, rabbits, pocket pets, reptiles, birds, and one memorable lion cub. She lives in Southern California with her husband, two sons, and miniature poodle Jäger, who she grooms at home.  Jackie can be reached at jackiebrownwriter.Wordpress.Com. Learn more about how our team of experts tests and reviews products at Insider here. Read more Read less

JoAnna Pendergrass, DVM

Freelance Contributor

JoAnna Pendergrass, DVM, is a veterinarian and founder of JPen Communications, a medical communications company that specializes in pet owner education. Her expertise extends across many areas of veterinary medicine, including preventive pet care, nutrition, and common (and not-so-common) dog and cat diseases. Dr. Pendergrass earned her veterinary degree from the Virginia-Maryland College of Veterinary Medicine, then completed a research fellowship at Emory University's Yerkes National Primate Research Center. During this fellowship, she decided to combine her love of science and writing by becoming a medical writer. After working at medical communications agencies for several years, Dr. Pendergrass transitioned to freelancing. She currently writes for several veterinary publications, including Great Pet Care, Healthy Paws Pet Insurance, and All About Cats. She has previously written for PetMD, Pet Coach, dvm360, and American Veterinarian.  Dr. Pendergrass can be reached at http://www.Jpencmc.Com. Read more Read less

Man Blames Popular Flea And Tick Medication For His Beloved Dog's Death

WINDHAM, Ohio (WOIO/Gray News) - An Ohio man blames a flea and tick medication for the death of his dog, saying his veterinarian didn't warn him about the possible side effects.

Ted DeSalvo's dog, 3-year-old Greta, was euthanized last month. He blames her death on Simparica Trio, a chewable tablet used to protect dogs against heartworm disease, ticks and fleas.

"She was a companion to me," DeSalvo told WOIO. "She was murdered in my view. She was murdered by this product."

Greta had a chewable Simparica tablet June 1. The next day, she had seizures. She had been taking the medication once a month for two years.

"Usually, she runs out of her crate, but this time, she didn't run out; she hesitated. We looked inside, and she was shaking. She was having seizures," DeSalvo said.

He immediately took Greta to the vet, where he says he was told it was a "neurological issue."

"We asked about the medication then, and at that time, she did admit ... She's seen that product do that to other dogs," DeSalvo said.

Greta progressively got worse over time, and her owner was forced to put her down.

"She had no action. She was dead weight," DeSalvo said.

DeSalvo claims his vet didn't initially warn him about the possible side effects of Simparica. On the back of the box, it says adverse reactions may include tremors, ataxia and seizures due to the ingredient sarolaner.

"Use with caution in dogs with a history of seizures or neurologic disorders," the box reads.

DeSalvo says Greta had neither before this incident.

"This was not explained to us. This is not explainable that it was neurological, that it wasn't the product," he said.

WOIO called the vet but did not hear back.

The Food and Drug Administration put out a fact sheet about adverse events associated with isoxazoline flea and tick products in August 2023. Simparica Trio is in the isoxazoline class. The FDA says while the products can and have been safely used in the majority of cats and dogs, pet owners should still consult with their vet to determine what product is best for them.

Zoetis is the company that makes Simparica Trio. In 2022, it put out a statement responding to another dog's death after a pet owner took their frustration to social media.

The company said:

"We are confident that Simparica Trio, which has been prescribed to protect over 10 million dogs since coming to the U.S. Market in 2020, remains an effective and safe parasite preventative option for most dogs."

DeSalvo warns other dog owners to research every product before giving it to your dog and always ask questions.

"Why are those warnings on the box if it's safe?" he said.

WOIO reached out to Zoetis. The company says they have spoken to DeSalvo and are investigating Greta's death.

The company also released a statement:

"We are committed to providing safe and effective products to veterinarians, pet owners and the animals in their care, and we sympathize with fellow pet owners when they experience a loss. We take the reporting of any adverse event very seriously, and our team works to understand each situation."


Why Is Zoetis (ZTS) Up 1.4% Since Last Earnings Report?

It has been about a month since the last earnings report for Zoetis (ZTS). Shares have added about 1.4% in that time frame, underperforming the S&P 500.

Will the recent positive trend continue leading up to its next earnings release, or is Zoetis due for a pullback? Before we dive into how investors and analysts have reacted as of late, let's take a quick look at its most recent earnings report in order to get a better handle on the important drivers.

Zoetis Q2 Earnings & Revenues Beat, '24 Outlook Raised

Zoetisdelivered second-quarter 2024 adjusted earnings (excluding one-time items) of $1.56 per share, which surpassed the Zacks Consensus Estimate of $1.49. In the year-ago quarter, the company delivered adjusted earnings of $1.41 per share.

Total revenues grew 8% year over year to $2.36 billion in the reported quarter, which also beat the Zacks Consensus Estimate of $2.30 billion. In the year-ago quarter, the company reported total revenues of $2.18 billion.

Quarterly Highlights

Zoetis derives the majority of its revenues from a diversified product portfolio of medicines and vaccines used to treat and protect livestock and companion animals. The company reports business results under two geographical operating segments — the United States and International.

Revenues from the U.S. Segment increased 12% year over year to $1.31 billion in the reported quarter, beating both the Zacks Consensus Estimate as well as our model estimate of $1.26 billion.

Sales of companion animal products in the U.S. Region jumped 13% from the prior-year quarter's level to $1.08 billion, driven by Zoetis' monoclonal antibody products for osteoarthritis (OA) pain, Librela for dogs and Solensiafor cats, as well as its flea, tick and heartworm combination product for dogs, Simparica Trio. The uptick was also fueled by the company's key dermatology portfolio, including Apoqueland Cytopoint.

Sales of livestock products in the United States increased 11% in the second quarter to $228 million, mainly driven by higher sales ofcattle and swine products due to favorable timing of supply of ceftiofur compared with the year-ago quarter.

Revenues in the International segment improved 4% year over year on a reported basis and 10% on an operational basis to $1.04 billion, beating both the Zacks Consensus Estimate and our model estimate of $1.02 billion.

Sales of companion animal products rose 7% on a reported basis and 12% on an operational basis, driven by growth in several key products. These included OA pain products, Librela for dogs and Solensia for cats, dermatology products like Apoquel and Cytopoint, as well as Zoetis' parasiticide products, such as Simparica and the Simparica Trio.

Story continues

On a year-over-year basis, livestock product sales were flat on a reported basis but grew 8% operationally. Growth in both the cattle and poultry portfolios was driven largely by price increases across the broader international segment. Additionally, sales of fish products grew due to increased demand for vaccines in Norway.

2024 Guidance Raised

Zoetis now expects adjusted earnings in the range of $5.78-$5.88 per share in 2024 compared with the previous guidance of 5.71-$5.81 per share.

Revenues are projected between $9.10 billion and $9.25 billion, suggesting an operational growth of 9-11%. Total revenues were previously projected between $9.05 billion and $9.2 billion.

How Have Estimates Been Moving Since Then?

In the past month, investors have witnessed a downward trend in fresh estimates.

VGM Scores

At this time, Zoetis has a subpar Growth Score of D, a grade with the same score on the momentum front. Following the exact same course, the stock was allocated a grade of D on the value side, putting it in the bottom 40% for this investment strategy.

Overall, the stock has an aggregate VGM Score of D. If you aren't focused on one strategy, this score is the one you should be interested in.

Outlook

Estimates have been broadly trending downward for the stock, and the magnitude of these revisions indicates a downward shift. Notably, Zoetis has a Zacks Rank #3 (Hold). We expect an in-line return from the stock in the next few months.

Performance of an Industry Player

Zoetis is part of the Zacks Medical - Drugs industry. Over the past month, Ionis Pharmaceuticals (IONS), a stock from the same industry, has gained 1.8%. The company reported its results for the quarter ended June 2024 more than a month ago.

Ionis Pharmaceuticals reported revenues of $225 million in the last reported quarter, representing a year-over-year change of +19.7%. EPS of -$0.45 for the same period compares with -$0.60 a year ago.

For the current quarter, Ionis Pharmaceuticals is expected to post a loss of $1.17 per share, indicating a change of -13.6% from the year-ago quarter. The Zacks Consensus Estimate has changed -0.1% over the last 30 days.

The overall direction and magnitude of estimate revisions translate into a Zacks Rank #3 (Hold) for Ionis Pharmaceuticals. Also, the stock has a VGM Score of F.

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